Important to point out that Chisel/Semi-chisel refers to the shape of the cutter and not the anti-kickback properties of the chain. Semi Chisel is not necessarily "safety" chain and there are full-chisel "safety" chains. Note from here on out I will refer to "safety" chain as "green label" chain.
Green label chain has one or more of the following to reduce kickback tendencies:
One example given for each feature.
A.) Folded over raker/depth gauge (Oregon Vangaurd)
B.) Single-humped drive links (Stihl RSC3)
C.) Raised tie-straps (Stihl RM2)
Obviously, green label chain dominates the box-store shelves. The single humped drive link varieties are not bad at all and if the nose of the bar is not buried in the wood, they cut comparable to a "pro" chain. That said, if I'm plunking down cash for a chain, it's yellow label 99.9% of the time.
Thistle is right in that most shops do not charge a premium for yellow-label chain (usually the cost is less to them, chain is simpler and has fewer parts) so no cost disadvantage there.
The yellow label chain you hear us all yak about on here is sold through most power equipment dealers and saw shops. There are both full and semi-chisel varieties, sometimes they are called "chisel" and "chipper" chains. We talk the most about full chisel chain here as it is the fastest cutting. It also will require more frequent sharpening than semi-chisel and is very intolerant of dirt/rocks/metal. That's because full-chisel has a very sharp leading point on the cutter and the cutting efficiency of the chain is very dependent on those points. Semi on the other hand, has a rounded cutter with a long, knife-like edge that not only holds it's edge longer, but small imperfections do not drastically slow the cutting action down like they do with full-chisel.
Of course we could talk at you for pages about chain, lots to discuss, carbide, square ground, skip chain, ripping chain, oh yes it gets fun....