I've been told to ask any bald headed guy about radiant heat in a ceiling. They don't like it. I am just about on the edge of qualifying to comment
I think the issue with any heating system is how well the space is insulated. In ceiling radiant was quite popular at one point but that was on houses built to a far lower energy standard. I expect the old systems really had to crank out the BTUs which meant high supply temperatures to make up for heat loss through marginally insulated walls, concrete slabs and single pane windows. I know of at least one person who went with wall and ceiling radiant in a kitchen addition and was quite happy. Since the typical room is much tighter now, I expect the supply temps are far lower thus making it less of issue with those who are follicle challenged. The picture hanger issue is just matter of common sense, use a stud finder and put the nails in the studs.
As an aside I remember my dad wanting to install 6" insulation in the walls when we finished a second floor space around 1970, the building supply stores had to special order anything thicker than 3.5" and the standard recommendation was not to go anything thicker as we would rot out the walls. Many walls of that era used 2" or less and in more southern areas they used none. If energy was cheap why spend the money to insulate?